Alice v CLS (2014) was a landmark case for patent eligibility. The decision held that Alice’s patents were invalid because the claims were drawn to an abstract idea and implementing them on a computer wasn’t enough to transform the abstract idea into patentable subject matter.
The Supreme Court saw numerous patent related cases in the wake of Alice, but since then there has been much less focus on patent matters. 2014 saw 6 patent related matters appear, Alice being the first. The subsequent years saw:
2015 3 cases
2016 2 cases
2017 0 cases
2018 3 cases
2019 3 cases
2020 1 case
2021 2 cases
https://en.wikipedia.org/wiki/List_of_United_States_Supreme_Court_patent_case_law